The Mesets resembles a human-sized crow in appearance and has the ability to fly and chase after their prey. Its behavior is similar to a common crow however, it possesses a greater intelligence than most mutations, choosing to attack its victims when they are distracted by other dangers. Its main venue of attack is to grab its victim and after reaching a certain height, drop them, which causes moderate damage. A Mesets will also try to rake opponents with its razor sharp talons. Mesets are a very rare mutation, only emerging from specific chrysalids during Jake and Sherry's search for the data files in the Edonian mountains, although Neo-Umbrella J'avo occasionally transform into them. The Mesets' head, strangely, is not avian-shaped at all, and is positioned upside down.
For some reason, the Mesets are vulnerable to flash grenades. Simply blinding them with a flash grenade is enough to instantly kill them, likely because the bright UV light emitted from the grenade causes the creature to lose flight balance, immediately killing them once they crashed to the ground.
The Mesets relies on being airborne to sneak up on an unaware victim. Its only known attacks are slashing with its talons and grabbing its prey, carrying them upwards and dropping them, causing medium damage. In higher difficulties they will grab the player, causing a QTE event that will result in the player being thrown down the pits on Jake and Sherry's campaign. A unique counter for either character can then be initiated, usually resulting in a one hit kill.
When it appears in Jake's campaign, the harsh snowstorm makes it very hard to see in such situations. When encountering these for the first time, it is recommended to let the snowstorm settle for a clear visual. These creatures are usually airborne however, they will land sometimes, attempting to sneak up on the player. When the snowstorm has settled, focus on the Mesets when they are airborne. Using Jake's Nine-Oh-Nine or Sherry's Triple Shot, unload on them until they go down. The same method applies on the ones that have landed.
The Mesets that spawn from Neo-Umbrella J'avo can be eliminated the same way, but extra caution is advised if there are other J'avo or B.O.W.s present. Mesets are also very vulnerable to flash grenades, which can eliminate multiple at one time if they're in close proximity to each other.