Resident Evil Zero, known in Japan as biohazard 0 (バイオハザード０), is a survival horror game that was developed and published by Capcom for the Nintendo GameCube and released in 2002. It is the fifth game in the Resident Evil series by release order and was the last of the core titles to use the original Multi-View gameplay system prior to the release of Resident Evil 4.
A remastered, high definition version of the game is set to be released in 2016.
The game's storyline serves as a prequel to the original Resident Evil, covering Rebecca Chambers' ordeal a day prior to the Arklay Laboratory incident.
Faced with the relentless undead and other horrifying creatures, S.T.A.R.S. officer Rebecca Chambers makes an alliance with Billy Coen, an escaped criminal. Unknowingly, Rebecca stumbles into the prelude of an event where she will be tested to her limits and her greatest fears will be realized. Together, Billy and Rebecca must survive the nightmare and expose the dark secrets of what has caused it.
Rebecca Chambers - An 18 year old rookie medic from the S.T.A.R.S.Bravo Team. She is on her first mission, investigating the mysterious murders plaguing the Arklay Mountains. Mission priority is shifted over to the apprehension of Billy Coen when the team learns of his escape. She separates from the team and discovers the Ecliptic Express train stopped on the tracks. As she enters to search for survivors, the train starts to move again after two members of the U.S.S. Delta Team restart the train.
Billy Coen - A former United States Marine convicted of murder, he was sentenced to death and on his way to his execution when mysterious events allowed him to escape into the forest and to the nearby Ecliptic Express train.
James Marcus - A brilliant scientist and one of the three founding members of Umbrella. He was the company's top researcher until he mysteriously disappeared over twenty years ago.
William Birkin - Although much younger than James Marcus, William is just as brilliant and is a genius in the science & research department. Birkin is highly ambitious and shows great interest in Marcus' work.
Enrico Marini - The captain of S.T.A.R.S. Bravo Team, he is in command of Rebecca and leads the search for Coen. He cares very deeply for all those under his command, but he has become suspicious of the circumstances that have led them to this situation.
Edward Dewey - A member of S.T.A.R.S. Bravo team who served as the helicopter co-pilot. He, like the other Bravo team members, is searching for Billy Coen in the forest. He is the only other member of the Team, including Rebecca, to enter the Ecliptic Express. He was killed by Cerberus and was seen eating a dead body as a zombie when Rebecca and Billy tried to stop the train.
A novelization of the game titled Resident Evil: Zero Hour was written by author S.D. Perry. It was the seventh book of the Resident Evil series but preceded all the other books in terms of chronological order. A prequel to the very first game (Resident Evil) or book (Resident Evil: The Umbrella Conspiracy), the main characters include the Bravo Team's Rebecca Chambers and an ex-Marine named Billy Coen.