|Based:||Human, Tyrant series|
|Created via:||Tyrant with cybernetic Experimentation|
The Tyrant R was equipped with various cybernetic components; It could be programmed for various objectives, and was outfitted with a small but powerful explosive in its neck. Its durability was far greater than that of other Tyrants, and so even a rocket launcher would only knock it unconscious rather than blow it to pieces.
Prior to the Raccoon City Destruction Incident, Hunters were being created in large numbers (via the Nursery, or by transportation) to combat the Tyrant R in a number of strength tests. However, the Tyrant still hadn't been activated by the time of the Outbreak, and the Hunters escaped.
The Tyrant was activated at the early hours of October 1st by Umbrella scientist Dr.Carter to combat the renegade Hunter Rs lost in the facility. Just prior to the escape of the survivors in the lab, the Tyrant became self aware, killing Carter, destroying the Tyrant virus vaccine and knocking both Linda and the detonator for its internal bomb off a catwalk.
After chasing David King and Linda through the ruined city and mutating into a more powerful stage, the Tyrant arrived at the highway overpass and was ready to attack David. Suddenly, Nyx grabbed hold of and absorbed it into its body. Nyx was destroyed by David and it was set free again. It then confronted Ada Wong, another fleeing survivor, who defeated it with ease, identifying it as "clever, but predictable". Ada killed the monster for good.
- This Tyrant displays intelligence unseen in most of its brethren: it actually took the time to hunt down and kill Carter, who was the one who held the switch to its internal bomb and posed the greatest threat to it at the time. This Tyrant has also been able to go into a fast state along with absorbing less damage as seen in Resident Evil: The Umbrella Chronicles. In the Umbrella Chronicles it is revealed that this Tyrant can jump an amazing distance.
- Considering its remarkable intelligence, it may have been an attempt to match Umbrella Europe's famed Nemesis project.
- It has an instant death attack in Normal, Hard and Very Hard difficulties. It is easily noticeable for the player because it will start to groan and balance its arms fast, cutting its victim multiple times in the process.
- During the short period it is an ally, it can be hurt by the player, but it will not die until it goes berserk at the survivors.
- During "End of the road", a player can kill the Tyrant R with the detonator on several occasions in order to obtain event check list points. Since the detonator is good for one use only, the level has to be played 3 times to achieve them all:
- Inside of the unnamed Umbrella's facility.
- In the streets while it chases the survivors.
- While fighting Nyx (it won't kill the creature, but it causes its "heart" to open for players to shoot at it).