- Umbrella is founded as a way of selling bioweapons to the US military to get money to fund their eugenics program. All variants of Progenitor to be used as WMDs are called "t-Virus". Oswell E. Spencer; James Marcus and Edward Ashford each begin research into Progenitor with the aim of developing bioweapons from it.
- The cable trolleys that circulate around Raccoon City are built and imported from Europe.
- The managing director of the Incineration Disposal Plant P-12A" is born.
James Marcus is chosen by Spencer to become the director of the Research Center within the Arklay Mountains. Marcus does not care for a job of training new employees but chooses the job anyway as a place of conducting his experiments.
Marcus writes in his journal about his latest argument with Spencer over the development of the Progenitor virus.