"In July of 201X there is a series of large-scale attacks on cities across the globe, with many cities losing their function. The bioterrorism disaster that began with Umbrella's bioweapons development incident has entered a new stage. People in the isolated town tremble with fear at the creatures' attacks. With the initial failure against the bioterrorist organizations, various leaders decided to give authority to the restructured teams. You are a leader; form a courageous team to encounter the mess in the town!"
— Approximate translation of the official website's plot summary.