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The Bell Boeing V-22 Osprey is a military tiltrotor aircraft. The Umbrella Corporation possessed a fleet of these aircraft in the 21st century, which they used for military operations after the 2002 global T-virus pandemic. Six months after Umbrella's makeshift headquarters in Tokyo was destroyed, Umbrella Prime sent in a number of Ospreys to attack the Arcadia.
While the Osprey was first produced in 1988, no real-world military incorporated it into their air fleets until 2005, three years after the global T-virus pandemic would have begun.