"Brian Irons" may refer to the following:
- "Brian Irons" - the Prime Brian who lives in the Mainsteam universe.
- "Brian Irons" - a mirror of the Mainstream Brian who lives in the Perryverse.
- "Brian Irons" - a mirror of the Mainsteam Brian who lives in King's Foundation's universe.
- "Brian Irons" - an in-game file in Resident Evil: The Darkside Chronicles.
- "Brian Irons" - a mirror of the Mainsteam Brian who lives in WildStorm's universe.
- "Brian Irons" - a mirror of the Mainsteam Brian in the book of Resident Evil: The Beginning Universe.
- "Brian Irons"