Aside from their fly-like appearance, the Chimera's most notable characteristics is their ability to walk over walls and ceilings. They usually use the air ducts to travel from one part of the lab to the other and attack with their claw-like limbs. When killed, a chemical imbalance in their bodies causes them to dissolve.
They cannot fly because of the lack of size of their wings, and they lacked a fully developed exoskeleton. Even though they showed signs of notable resilience, their intelligence was little more than that of an insect. Their bodies also hosted a large number of maggots.