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Director's Diary, known as the "memoirs of the head doctor" (医院長の手記 Iin-chō no shuki ) in the original script, is a file that can be found in Resident Evil 3: Nemesis.
These patients suffer from gangrene and congestion of their blood at first. Then their mind slowly deteriorates. In the end, there is nothing left of their Mind. When that happens even mercy killing seems pointless. After all, they are already dead...
This disease is unlike anything I have ever witnessed. Once the patient's mind is gone, they become flesh hunger monsters and act like wild animals who are on some type of bloodlust.
Another patient has been admitted to the hospital. He is showing symptoms of the first stages of the disease at this point, but... I haven't been able to sleep at all these past few days. I refuse to let these patients become "Zombies." I am not just an ordinary citizen. I am a doctor. Even if I die, my clinical charts will contribute to finding a cure.
We lost most of the doctors and staff during the battle against the "zombie" patients. It's impossible to maintain the hospital under these conditions. And, I know that it's too late for me. I am beginning to feel that same itchy and hungry desire that all of my patients felt. It's too late for me...
そろそれ辛い。 わたしの 意識も もも もたな る
Initial symptoms regularly develop from necrosis of the skin and blood congestion to a turbid volition, and finally even lose human reason. In that case, recovery is hopeless and even euthanasia does not apply. It's obvious. That patient should have been clinically dead already. It is a dreadful disease. The patient loses reason and violence is like severe drug addiction. Like a hungry tiger, they crave raw flesh and attack.