The Durga's weak point is the exposed core in its chest which it will attempt to shield using the arms hanging from its front. The player can either shoot the core between the gaps or destroy the arms themselves. The latter of which can be a risky strategy as the Durga will enter a berserk state where it will increase its speed and attempt to ensnare the player with its claw which results in an instant kill.
As with all Uroboros mutations, the Durga is very vulnerable to fire, it should be noted however that using fire will attack the creature as a whole, meaning it will destroy the body parts, which will cause it to enter its "berserk" mode.
Using a Smokescreen Bottle allows the player to do a melee attack on a Durga. After the attack, it's possible to knife the orange core until the monster gets up and can be easily finished with any firearm.
Another strategy is to use its frontal tentacle attack against it. Its patterns can be summed up into these:
If you're facing it, it'll raise its tentacle and brings it downwards.
If you go to the sides, it'll do sweep attacks.
If you're a little far away, it'll jump and then a quick attack similar to (1) or (2).
Shoot one of its 4 arms will make it go berserk, meaning it'll use its insta-kill attack.
Sometimes, even if you don't shoot its arms, it'll still go berserk.
You'll notice when it's about to do its insta-kill when it lowers its posture and raises its arms a little. Stay away until it stops.
All you need to do is grab your magnum, rifle or shotgun, aim towards its weak spot and approach it from the front. It'll do (1), but just when its weak spot is exposed, shoot. There's a good chance it'll interrupt it but sometimes it won't flinch. You can attempt a second shot to stagger it but if you want to play it safely just dodge after each shot.
Approach, shoot, dodge, repeat.[1]
