This page is not intended for generic trivia - defined here. It is only a placeholder for notable information not yet placed into other sections. When a point has been inserted elsewhere in the page, remove it.
The sounds coming from the mines inside the first El Gigante's enclosure are actually the roars of a lion.
In some versions of the game, if you hit El Gigante with the Rocket Launcher as he grabs you, when he dies you will also despawn, making you unable to do anything.
During early stages of development of Resident Evil 5, at one point, Tricell was planned to release 10-15 El Gigantes into the African town. The Art of Resident Evil 5 contains rough concept art of this scrapped invasion.
In the Mobile Edition Leon does not have the option to knife the plaga in their backs. Instead the enemy is defeated by simply damaging it enough.