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" You can combine this item with others to make various sub-weapons."
— Item examination.

Empty Bottle is a combine item in Resident Evil: Revelations 2.

Creating Sub-weapons

The empty bottle can be used to create different sub-weapons by combining it with different materials:

Sub-Weapons Combine with
Exploding Bottle  + Gun Powder
Firebomb Bottle Alcohol
Decoy Bottle Odorous Chemical
Smokescreen Bottle Smoke Powder

Bibliography

Sources