(Covers information from the S.D. Perry novels)
Dr. James Trenton Darius was a microbiologist who worked for the Umbrella Corporation during its early years.
James and his pharmacologist wife, Helen developed a method of reengineering viruses to treat injuries. Umbrella was impressed with their research, but was unwilling to mass-produce it since a healthier population would be detrimental to the pharmaceuticals industry. Instead, they planned to use their research for the military. When James and Helen showed signs of disapproval, Umbrella had Dr. William Birkin collect their research notes and then killed the couple in an elaborate "accident" involving a fire. After their deaths, their son Victor became obsessed with seeking revenge. Victor changes his name to "Trent" in his father's honour.