Mainstream universe
(Capcom's primary storyline)

Louise was the older sister of Amy.[note 1] When the two girls were young, they were involved in a car crash, which killed their mother.

Amy wrote a letter to Louise shortly before the Raccoon City Destruction Incident became noticeable.[1]


  1. The Japanese version of the file establishes twice that Louise is the older sister, using the word onēsan (姉さん?): a noun used when talking to one's older sister.
  1. Resident Evil Outbreak (2003), file: "Guest Memo 2"

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