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The Medusa is a large Hunter featured in Resident Evil: Revelations 2's Raid Mode as part of the Huge Creatures online event.

Gameplay

The Medusa is a "Huge Creature", that walks slowly towards the player avatars, alongside the Stheno and the Euryale. The damage inflicted on the creature's enormous HP is accumulated through all the online players damage, making defeating them a cooperative effort between all Raid Mode players.

Sources