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Neptune Notes is a file that can be found in Resident Evil: The Umbrella Chronicles.
A new form of B.O.W. created from a Great White Shark base. It was developed as an experiment to prove that the T-virus would combine well with sea creatures.
However, the introduction of the T-virus provided only minimal enhancement to the pre-existing strength of the shark, and the result could hardly be employed as a true B.O.W. In the sea, it knows no enemies, but on land, it is powerless.