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The Proto Tyrant (T-001 Model) appears in the following titles.
| Name | Year | Format |
|---|---|---|
| Resident Evil 0 | 2002 | Video game |
| Resident Evil: Zero Hour | 2004 | Novel |
| Resident Evil: The Umbrella Chronicles | 2007 | Video game |
| Minna to BIOHAZARD Clan Master | 2012 | Mobile game |
| CR biohazard 0 | 2016 | Pachislot game |
| TEPPEN | 2019 | Mobile game |