Puppetmasters 1 is an article in Resident Evil Recollections. It was uploaded on 28 March 2016.
In Resident Evil 0, Wesker and William are busy behind the scenes as they attempt to cover up the virus outbreak.
Although Rebecca and Billy aren't aware of their presence, the story has a deep connection to the Mansion Incident.
Wesker takes this opportunity to finally sever his ties with Umbrella, as he enacts his plan to lure S.T.A.R.S. to the mansion.
Wesker must have a lot of faith in his own abilities to just get up and leave his employer of so many years, it's actually quite impressive...