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Along with Resident Evil Zero, the game came out for the Nintendo Wii on June 23, 2009 as part of the Resident Evil Archives. As with Resident Evil 4 Wii edition game, the game was outfitted with Wii pointer controls.
When the player is inside the mansion, there is a thunderstorm outside, but it disappears completely when the player goes outdoors.
It's the only game in which the Rocket Launcher doesn't instantly kill a zombie in one shot.
Staircase camera angles had to be changed when it became apparent that the designers had chosen to add Jill's civilian clothes of Resident Evil 3: Nemesis as an unlockable costume so they could look up her skirt. The color of her underwear was also debated upon during design when the water fountain reflections were found to show them; in the end, "black" won.
Director Shinji Mikami was used by the motion capture crew to represent white-shirted zombies.
Unlike The Original you can now run up and down the stairs freely instead of pressing the action button near them. This would simply mean that, they would have discarded all of the original 1st person cut scenes as far as going up or down the steps.
There is an amusing easter egg with the computer lab in which you must enter the passwords. When trying to unlock the B2F door, if you enter "Mole", the correct password that was used in the original Resident Evil game, you will hear Tofu speaking. This will not unlock the B2F door though.
The unlockable Real Survivor mode revolves around playing the game with auto-aim disabled and that all item boxes are no longer linked, forcing players to back track to a specific item box than visiting any of them. This concept was initially to be used in the original Resident Evil before it was scrapped, but resurfaced in this version. The unlock screen for this mode even explains the original concept for the game.
Gametrailers rated this game in particular #3 in their scariest games countdown in 2006.