In Alexander's Memo, Edward Ashford is said to have performed extensive research on the Progenitor Virus. In the localization, he and Oswell E. Spencer mutually performed this research on the virus, referred to here as the "Mother Virus". While the Japanese script indicates that a mutated strain of the virus is now called the "t-Virus", the localization suggests that it was Spencer and Ashford that gave it its name. While Umbrella is referred to as "Umbrella Pharmaceuticals", the localization changes it to "Umbrella Chemical, Inc.". Alexander is said to have specialized in Genetic Engineering in the Japanese script, though the localization states that he Majored in University at "biogenetics".
The Newspaper Clip in the Japanese script describes how Alexia Ashford graduated from a prestigious university at the age of ten, and is now being considered for a job at Umbrella Pharmaceuticals as a senior researcher. In the localization, she is said to have graduated "top of her class", and has been offered the position of the more-definitive-sounding "head researcher". Again, it replaces "Umbrella Pharmaceuticals" with "Umbrella Chemical, Inc."
The Butler's Letter is one of several files which demonstrate a lack of understanding of the non-heritability of knighthood. While there are certain people with a hereditary status styled 'Sir', they are baronets, not aristocrats ('lords'). As the word for "Lord" and "Sir" is the same in Japanese, "卿", it should be accepted that all usages of "Sir" when referring to the Ashford family are mistranslations of "Lord". Anatomist's Note, which refers to Alfred as "Mr." in the original script, was translated to refer to him as "Sir", again.
In the Worker's Diary, the November 3 entry has the unnamed worker express his dissatisfaction towards Alfred Ashford. In the original script, he criticises Alfred's apparent incompetence as facility director; in the localization, he states that Alfred doesn't deserve forgiveness for cancelling his vacation time, as he feels he wasn't treated as a human being.
While the Alloy Report refers to a "corrosion-resistant" alloy, its localization refers to its property as "anti-decay".
The TG-01 Product Description was expanded in one section to further explain the meaning of "entry/exit"; that is, the gates and terminals in airports (particularly international).