S.T.A.R.S. may refer to:
- Special Tactics and Rescue Service - A elite special forces team first appearing in Resident Evil.
- Special Tactics And Rescue Service (Perry) - The S.D. Perry novel incarnation based on the game.
- Special Tactics And Rescue Squad - The incarnation of the Paul W. S. Anderson movies based on the game.
- S.T.A.R.S. (Wildstorm) - The DC Comics incarnation.
- S.T.A.R.S. (Romero) - The incarnation in the undeveloped script by George A. Romero.