(Capcom's primary storyline)
For much of its existence, the Sacred Snakes' primary criminal enterprise was drug trafficking. Through the murder of nearby rivals, the Snakes were able to dominate much of the Amazon and, with influence over law enforcement, their only major threat were Communist guerillas. The local town of Amparo held great respect for the group due to Javier Hidalgo's generous reputation and investment in the region. In the early 2000s the Sacred Snakes began amassing a force of Bio Organic Weapons for use against the Communist guerillas; the project, "CODE:REMNANTS", required the abduction of humans for test subjects as well as trafficking of slaves. With the Snakes possessing bio-weaponry and indicating a willingness to use them, a number of nations began calling for Javier's overthrow.
In 2002 the Snakes, under Javier's orders, began releasing their B.O.W.s into the wilderness.