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"A LONELY, INSECURE 12-YEAR-OLD, SHERRY IS QUITE MATURE FOR HER AGE. SHE IS VERY SHY AND WHEN SHE SPEAKS, SHE LACKS SELF-CONFIDENCE AND ALWAYS HAS THE FEELING SHE IS LOST. HER PARENTS ARE TOO WRAPPED UP IN THEIR WORK TO HEED THE EMOTIONAL NEEDS OF THEIR CHILD."
— Resident Evil 2 Nintendo 64 Manual, p.3
Sherry's model appears to differ in Darkside Chronicles between gameplay and cutscenes. Her hair appears darker, almost brown, in gameplay but becomes the usual blonde in cutscenes. Also, her headband appears red in gameplay and pink in cutscenes.
Wesker's Report stated that Sherry was 'safe' in his hands, implying she was under his custody. However, the "Inside of Biohazard The Darkside Chronicles" book provided closure on this plot point by explaining that Wesker simply had spies in the government keeping an eye on her.
In the Echo Six DLC of Operation Raccoon City, Sherry becomes aware that the creature chasing her is her father, William Birkin, something that didn't occur during the events of the original game. She did, however, learn of his identity afterwards as she is shown recalling his mutation as an adult in Resident Evil 6.