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The Silencer is an item which was twice removed from the games.
The Silencer in Zero is present on the biohazard 0 TRIAL EDITION disk, and was removed from the game at some point after its manufacture.
In the Shinji Mikami design for Resident Evil 4, Leon was also supposed to be able to originally obtain a silencer in Resident Evil 4 but for some reason the silencer was removed from the main game. However, the Silencer was recycled for Wesker's loadout in Resident Evil 4's Mercenaries minigame and appears on his handgun.