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(Covers information from the S.D. Perry novels)
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Trisquads were an experimental B.O.W. developed by the Umbrella facility at Caliban Cove, Maine. An attempt at making an intelligent zombie capable of following basic orders and carrying weaponry, the trisquds were used primarily for perimeter security.
The trisquads were used by the Caliban Cove facility for security, a job the somewhat mindless B.O.W.s took to very well. Trained, or more accurately, programmed to only engage in combat only when another team was incapacitated, their combat ineffectiveness was ultimately their undoing, as the S.T.A.R.S. managed to flank and destroy one complete squad without it returning fire. The entire series was ultimately wiped out by the S.T.A.R.S. Exeter Branch.
Development and Traits
Trisquads were developed using a special variant of the t-virus created by Doctor Nicolas Griffith, which created infected both resistant to the virus's normal cannibalistic and extremely impressionable. Trisquads were put through a series of vigorous (for a zombie) tests, often involving picture puzzles or riddles. While the rewards for these were probably something to ease the B.O.W.'s painful mutations, they were co-opted by a sympathetic Umbrella researcher in order to assist the S.T.A.R.S. team ultimately deployed to shut the facility down. They opted in groups of three (hence, trisquad), and there were at least four teams present at the Caliban Cove facility.
The trisquads were all armed with M-16 assault rifles (variant unknown, though likely the A1, as it was capable of fully-automatic fire). How well trained the B.O.W.s were with these weapons is unknown, though they seemed to have focused more on volume of fire rather than accuracy, and were ultimately outfought by the Exeter S.T.A.R.S. and their Berettas.
The trisquads weren't especially combat effective, and would only engage a hostile when another team became incapacitated. This left them extremely vulnerable to flanking movements, and they were generally outclassed by any thinking opponent. Likely, they would've been deployed in support of heavier Umbrella units, such as T-103 Tyrants or 3K Hunters.
The trisquads, despite not being tempted to take bites out of their opponents, were still vectors for the t-virus, and Rebecca forbade any of her teammates from using their weapons.
Whether or not Umbrella picked up the B.O.W. for use elsewhere is unknown, although none were found inside the Envirotest A facility, so this seems doubtful.