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Any advice for an expereinced noobie?

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I once had RE5, lost it and now want it back. I dont remember a single thing about the storyline, and had some questions.

1 Is it worth keeping the "basic" weapons on the first playthrough? (M92F, VZ61 etc)

2 Which bosses should I fight, and which should I run from?

3 Any points in the story where I can farm money/ammo?

4 Which weapon should I upgrade first?

5 Any points in the story I should save ammo/health packs for?

thanks

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