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Wesker Mode is a bonus game mode for PACHI-SLOT biohazard.
In this mode, the player takes control of either Chris Redfield or Jill Valentine and must defeat 49 enemies that Albert Wesker releases from within his hideout. Upon killing all 49 enemies, a cutscene is shown marking the taking down of 50 enemies where the player character bursts into Wesker's command center and proceeds to shoot Wesker in the shoulder just as he was about to shoot the player character, with the player then holding Wesker at gunpoint while he looks down in disappointment as the game tells the player that they won.